"The textbook Exploring Genetic Mechanisms is an
excellent account of the hallmarks of modern genetic
analysis...[It] takes its readers through a detailed account of
many fundamental principles of molecular genetics. It provides
specific examples of well-characterized genetic mechanisms that
operate within a gene family as well as examples of more complex
genetic relations that operate within an entire organism. This
book represents the next generation of modern genetics textbooks
and will be invaluable for genetics researchers and
--The New England Journal of Medicine
"In their earlier volumes, Singer & Berg have laid
out the fundamentals of modern molecular biology. Here, with a
group of the finest co-authors, they focus on the individual
stories that make biology such a rich and varied science. The
genes come alive as individual pieces of the biological tapestry.
Viral genes, hemoglobin genes, genes for antibodies, genes of
plants oncogenes and many more are probed along with the
methodologies used to investigate them. A great volume from which
to learn or teach about how actual life emerges from the four
bases that make up DNA."
--David Baltimore, President-Elect California Institute of Technology
"The currency of the coverage and the clarity of the
diagrams are wonderful. It is a rare delight to have such
complete coverage of the major topic areas written in such a
student-learning conducive manner...it will become one of the
--John Stubbs, San Francisco State University
"Like its two two predecessors (Dealing with Genes, and
Genes and Genomes), Exploring Genetic Mechanisms
shows the result of thoughtful organization of content and
careful editing. It succeeds in its purpose to familiarize the
reader with the many different ways molecular genetics is being
used to unravel and to understand the complex mechanisms involved
in the development of a living organism from a collection of
genes found in DNA...all chapters carry the superb writing style
of Singer and Berg, who provide the unifying overviews and
insights. The overall quality of Exploring Genetic Mechanisms
(and of Genes and Genomes) is such that both can
serve as models for any scientific work. Upper-division
undergraduates through professionals."
This integrated collection of case studies examines in detail how genes operate in systems. It can be used separately or as a companion volume to Genes and Genomes. An outstanding group of scientists have collaborated to develop this all-new 2-color text. It is recommended for students and professionals in biochemistry, molecular and cell biology, and genetics.
About the Authors:
Maxine Singer is the President of the Carnegie Institution of Washington and Scientist Emeritus at the NIH where she conducts research on transposable elements in the human genome. She is a member of the US National Academy of Sciences and its Institute of Medicine, and was awarded the National Medal of Science in 1992.
Paul Berg is Willson Professor of Biochemistry and Director of the Beckman Center for Molecular and Genetic Medicine, Stanford University School of Medicine. He is a member of the US National Academy of Sciences and its Institute of Medicine. He was awarded the Nobel Prize in Chemistry in 1980, and received the National Medal of Science in 1983.
Translated into Chinese.